| ncRNA name | SERPINA3K siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat retinal precursor cell line R28 |
| Methods | siRNA transfection, ELISA, Western blot, immunohistochemistry, immunostaining, MTT assay, qPCR, Glutathione assay, SOD assay |
| Expression pattern | associated |
| Functional description | SERPINA3K is an endogenous anti-inflammatory factor, and its anti-inflammatory effects may be mediated through antioxidant activity. Knockdown of SERPINA3K by siRNA resulted in the overexpression of VEGF and TNF-alpha in cultured retinal cells. |
| PubMed ID | 19324842 |
| Year | 2009 |
| Title | Anti-inflammatory and antioxidant effects of SERPINA3K in the retina. |
| Drug-related ncRNA | NO |
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